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Home > Product > Recombinant proteins > Recombinant Mouse MIP-1 Beta/CCL4 protein

Recombinant Mouse MIP-1 Beta/CCL4 protein

Recombinant Mouse MIP-1 Beta/CCL4 protein

Product Summary

Size: 10 ug,2 ug

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Source: Escherichia coli.

Product Summary

Size: 10 ug,2 ug

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Source: Escherichia coli.

Product overview

Product name

Recombinant Mouse MIP-1 Beta/CCL4 protein

Code

CD00297

Biological activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 20-100 ng/ml.

Endotoxin

Less than 1 EU/μg of rMuMIP-1β/CCL4 as determined by LAL method.

Synonyms

MIP-1β/CCL4,AT744., AT744.1, Act-, Act-2, MIP-, MIP-1B, Mip, Mip1b, Scy, Scya4, Mouse

Sequence

APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN

Uniprot Accession

Molecular Weight

Approximately 7.8 kDa, a single non-glycosylated polypeptide chain containing 69 amino acids.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Background

Chemokine (C-C motif) ligand 4, also known as Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a monokine with inflammatory and chemokinetic properties. Recombinant CCL4 induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). Furthermore, recombinant Mouse CCL4 contains 69 amino acids and it shares 77 % and 86 % a.a. sequence identity with human and rat CCL4. Both human and Mouse MIP-1α and MIP-1β are active on human and Mouse hematopoietic cells.

Storage

-20ºC

Research area

Immunology

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Associated products

  • Size

    Code

    Price

  • 10 ug

    CD00297

    $409.00

  • 2 ug

    CD00297

    $176.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our Recombinant proteins catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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