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Home > Product > Recombinant proteins > Recombinant Mouse FGF-10/KGF-2 protein

Recombinant Mouse FGF-10/KGF-2 protein

Recombinant Mouse FGF-10/KGF-2 protein

Product Summary

Size: 5 ug

Purity: > 95 % by SDS-PAGE and HPLC analyses.

Source: Escherichia coli.

Product Summary

Size: 5 ug

Purity: > 95 % by SDS-PAGE and HPLC analyses.

Source: Escherichia coli.

Product overview

Product name

Recombinant Mouse FGF-10/KGF-2 protein

Code

CD00457

Biological activity

Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 IU/mg.

Endotoxin

Less than 1 EU/μg of rMuKGF-2/FGF-10 as determined by LAL method.

Synonyms

FGF-10/KGF-2,FGF10,AEY1, AEY17, BB213776, Fgf-10, Fgf5a, Gsfaey, Gsfaey17, Mouse

Sequence

QALGQDMVSQ EATNCSSSSS SFSSPSSAGR HVRSYNHLQG DVRWRRLFSF TKYFLTIEKN GKVSGTKNED CPYSVLEITS VEIGVVAVKA INSNYYLAMN KKGKLYGSKE FNNDCKLKER IEENGYNTYA SFNWQHNGRQ MYVALNGKGA PRRGQKTRRK NTSAHFLPMT IQT

Uniprot Accession

Molecular Weight

Approximately19.5 kDa, a single non-glycosylated polypeptide chain containing 173 amino acids.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, 600 mM NaCl, pH 7.4, 1 mM mercaptoethanol.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Background

Fibroblast growth factor 10 belongs to the fibroblast growth factor (FGF) family, which is involved in a variety of biological processes such as embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Like most other FGF family members, FGF-10 also has a heparin-binding domain and plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. In addition, FGF-10 may take parts in wound healing and is required for normal branching morphogenesis. Recombinant Mouse FGF-10 contains a 173 amino acids and it shares 93 % and 90 % a.a. sequence identity with human and rat FGF-10.

Storage

-20ºC

Research area

Immunology

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Associated products

  • Size

    Code

    Price

  • 5 ug

    CD00457

    $176.00

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Lead time: Within two weeks

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