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Home > Product > Recombinant proteins > Recombinant Mouse Bcl-xL protein

Recombinant Mouse Bcl-xL protein

Recombinant Mouse Bcl-xL protein

Product Summary

Size: 10 ug,2 ug

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Source: Escherichia coli.

Product Summary

Size: 10 ug,2 ug

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Source: Escherichia coli.

Product overview

Product name

Recombinant Mouse Bcl-xL protein

Code

CD00616

Biological activity

Test in Process.

Endotoxin

Less than 0.1 EU/μg of rMuBcl-xL as determined by LAL method.

Synonyms

Bcl2l1, Bcl, Bcl(X, Bcl(X)L, Bcl-XL, Bcl2l, BclX, bcl-, bcl-x, bcl2-L-1, Mouse

Sequence

SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEET EAERETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIASWMA TYLNDHLEPW IQENGGWDTF VDLYGNNAAA ESRKGQERFN R

Uniprot Accession

Molecular Weight

Approximately 23.7 kDa, a single non-glycosylated polypeptide chain containing 211 amino acids.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4, 5 % Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Background

Bcl-xL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic, such as adult brain cells. It plays a role in the signal transduction pathway of the FAS-Ligand. Bcl-xL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers, and this is an significant event in the regulation of apoptosis. It is involved in the survival of cancer cells. Bcl-xL is the leading monitor of apoptosis/active cell suicide. It has cell death repressor activity and therefore acts as a survival protein. The Mouse Bcl-xL shares 97 % and 99 % a.a. sequence identity with human and rat Bcl-xL, respectively.

Storage

-20ºC

Research area

Cell Biology

Images

Protocols

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Associated products

  • Size

    Code

    Price

  • 10 ug

    CD00616

    $409.00

  • 2 ug

    CD00616

    $176.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our Recombinant proteins catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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