Product name
Recombinant Human MIA-2 protein
Code
CD01297
Biological activity
Data Not Available.
Endotoxin
Less than 1 EU/μg of rHuMIA2 as determined by LAL method.
Synonyms
MIA-2,MIA2,CTAGE5, MEA6, MGEA, MGEA11, MGEA6, TALI, Human
Sequence
LESTKLLADL KKCGDLECEA LINRVSAMRD YRGPDCRYLN FTKGEEISVY VKLAGEREDL WAGSKGKEFG YFPRDAVQIE EVFISEEIQM STKESDFLCL
Uniprot Accession
Molecular Weight
Approximately 11.4 kDa, a single non-glycosylated polypeptide chain containing 100 amino acids.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Background
Melanoma Inhibitor Activity Protein 2 (MIA2) encoded by MIA2 gene in humans, is a secreted cytokine that is highly expressed in liver and weakly in testis. The patients with severe fibrosis or inflammation and chronic hepatitis have higher level of MIA2 than other. Levels of MIA2 may severe as a clinically utility marker for diagnosis of hepatic disease activity and severity. The MIA2 is a member of the MIA/OTOR family, which also includes MIA, OTOR, and TANGO, and they share a Src homology-3 (SH3)-like domain.
Storage
-20ºC
Research area
Others
