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Home > Product > Recombinant proteins > SARS-CoV-2 S1 Recombinant protein (10xHis tag C-terminals, D614G)

SARS-CoV-2 S1 Recombinant protein (10xHis tag C-terminals, D614G)

SARS-CoV-2 S1 Recombinant protein (10xHis tag C-terminals, D614G)

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Product Summary

Size: 1mg,100ug

Purity: >90%, as determined by Coomassie blue stained SDS-PAGE

Source: Mammalian cell

Product Summary

Size: 1mg,100ug

Purity: >90%, as determined by Coomassie blue stained SDS-PAGE

Source: Mammalian cell

Product overview

Product name

SARS-CoV-2 S1 Recombinant protein (10xHis tag C-terminals, D614G)

Code

CD02455

Synonyms

COVID-19; 2019-nCoV; SARS-CoV-2; spike glycoprotein; 新型冠状病毒

Uniprot Accession

Molecular Weight

116 kDa

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Background

Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.

Storage

-20ºC

Research area

Microbiology

Images

Protocols

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  • Size

    Code

    Price

  • 1mg

    CD02455

    $5280.00

  • 100ug

    CD02455

    $1140.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our Recombinant proteins catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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