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Home > Product > Recombinant proteins > Recombinant Cynomolgus CDH3 Protein(C-His)

Recombinant Cynomolgus CDH3 Protein(C-His)

Recombinant Cynomolgus CDH3 Protein(C-His)

Product Summary

Size: 100 μg,500 μg,1 mg

Purity: > 95% as determined by Bis-Tris PAGE

Source: HEK293 Cells

Product Summary

Size: 100 μg,500 μg,1 mg

Purity: > 95% as determined by Bis-Tris PAGE

Source: HEK293 Cells

Product overview

Product name

Recombinant Cynomolgus CDH3 Protein(C-His)

Code

CD02464

Biological activity

The affinity constant of 0.37 uM as determined in SPR assay (Biacore T200).

Endotoxin

Less than 1EU per ug by the LAL method.

Synonyms

PCAD; CDHP; CAD3; Placental cadherin; HJMD; Cadherin-3; CDH3; P-cadherin; PCADP-cadherin

Sequence

Asp108-Gly654

Uniprot Accession

Molecular Weight

61.11 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Formulation

Lyophilized from 0.22um filtered solution in 20mM PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Background

Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been proved it could be a serum marker to monitor colorectal cancer. Inhibited CDH3 expression could upregulate E-cadherin, downregulated N-cadherin, which may control invasion and migration.

Storage

-20ºC

Research area

Others

Images

Cynomolgus CDH3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Anti-CDH3 Antibody captured on CM5 Chip via Protein A can bind Cynomolgus CDH3, His Tag with an affinity constant of 0.37 μM as determined in SPR assay (Biacore T200).

Protocols

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Associated products

  • Size

    Code

    Price

  • 100 μg

    CD02464

    $480.00

  • 500 μg

    CD02464

    $1920.00

  • 1 mg

    CD02464

    $3200.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our Recombinant proteins catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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