Product overview
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Background
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
Uniprot accession
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Recommended dilution
Application | Dilution |
---|---|
IF | 1:200 |
IHC | 1:100-200 |
WB | 1:1000-2000 |
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