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Home > Product > Antibody > Axl Monoclonal Antibody

Axl Monoclonal Antibody

Axl Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IF, ICC, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IF, ICC, ELISA

Product overview

Full product name

Tyrosine-protein kinase receptor UFO

Code

BT-MCA0198

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant extracellular fragment of human Axl fused with hIgGFc tag expressed in HEK293 cell line.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 558

Synonyms

AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene

Research area

Signal transduction; Cancer; Cell biology

Target protein

AXL

Recommended dilution

Application Dilution
ELISA 1:10000
IF 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using Axl Monoclonal antibody against extracellular domain of human AXL (aa19-444).
Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with AXL-hIgGFc using Axl Monoclonal antibody (green), showing cytoplasmic and membrane localization. Blue: DRAQ5 fluorescent DNA dye.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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