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Home > Product > Antibody > B23 Monoclonal Antibody

B23 Monoclonal Antibody

B23 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

Nucleophosmin

Code

BT-MCA0201

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human B23 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 4869

Synonyms

NPM1; NPM; Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin

Research area

Epigenetics and nuclear signaling

Target protein

NPM1

Recommended dilution

Application Dilution
ELISA 1:10000
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using B23 Monoclonal antibody against SMMC-7721 (1) HepG2 (2) HeLa (3) and HEK293 (4) cell lysate.
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissues, showing nuclear localization with DAB staining using B23 Monoclonal antibody.
Confocal immunofluorescence analysis of Hela (left) and NTERA-2 (right) cells using B23 Monoclonal antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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