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Home > Product > Antibody > Cyclin D3 Monoclonal Antibody

Cyclin D3 Monoclonal Antibody

Cyclin D3 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse

Applications: WB, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse

Applications: WB, ELISA

Product overview

Full product name

G1,S-specific cyclin-D3

Code

BT-MCA0397

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human Cyclin D3 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 896; Mouse: 12445

Synonyms

CCND3; G1; S-specific cyclin-D3

Research area

Epigenetics and nuclear signaling; Cell biology; Cancer

Target protein

CCND3

Recommended dilution

Application Dilution
ELISA 1:10000
WB 1:500 - 1:2000

Images

Western Blot analysis using Cyclin D3 Monoclonal antibody against NIH/3T3 (1) and Jurkat (2) cell lysate.

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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