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Home > Product > Antibody > GRK 2 Monoclonal Antibody

GRK 2 Monoclonal Antibody

GRK 2 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat, Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat,Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

Beta-adrenergic receptor kinase 1

Code

BT-MCA0630

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human GRK 2 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 15625238

Synonyms

ADRBK1; BARK; BARK1; GRK2; Beta-adrenergic receptor kinase 1; Beta-ARK-1; G-protein coupled receptor kinase 2

Research area

Signal transduction; Neuroscience

Target protein

ADRBK1

Recommended dilution

Application Dilution
ELISA 1:10000
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using GRK 2 Monoclonal antibody against HeLa (1) Jurkat (2) MOLT4 (3) RAJI (4) THP-1 (5) L1210 (6) Cos7 (7) PC-12 (8) and NIH/3T3 (9) cell lysate.
Immunohistochemistry analysis of paraffin-embedded endometrial cancer tissues (left) and cervical cancer tissues (right) with DAB staining using GRK 2 Monoclonal antibody.
Immunofluorescence analysis of NIH/3T3 cells using GRK 2 Monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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