Product overview
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Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
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Target protein
Recommended dilution
| Application | Dilution |
|---|---|
| ELISA | 1:10000 |
| FC | 1:200 - 1:400 |
| IHC | 1:200 - 1:1000 |
| WB | 1:500 - 1:2000 |
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