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Home > Product > Antibody > JAK3 Monoclonal Antibody

JAK3 Monoclonal Antibody

JAK3 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse

Applications: WB, IF, ICC, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse

Applications: WB, IF, ICC, FCM, ELISA

Product overview

Full product name

Tyrosine-protein kinase JAK3

Code

BT-MCA0798

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human JAK3 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 3718; Mouse: 16453

Synonyms

JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK

Research area

Signal transduction; Cancer; Epigenetics and nuclear signaling

Target protein

JAK3

Recommended dilution

Application Dilution
ELISA 1:10000
FC 1:200 - 1:400
IF 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using JAK3 Monoclonal antibody against Jurkat cell lysate (1).
Confocal immunofluorescence analysis of Hela (left) and HepG2 (right) cells using JAK3 Monoclonal antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Flow cytometric analysis of Hela cells using JAK3 Monoclonal antibody (blue) and negative control (red).

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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