Tel:86 021 3100 7137

Publish and get free product : share with us your publications using BT LAB product and get free products.
Home > Product > Antibody > Mi2- Alpha Monoclonal Antibody

Mi2- Alpha Monoclonal Antibody

Mi2- Alpha Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Product overview

Full product name

Chromodomain-helicase-DNA-binding protein 3

Code

BT-MCA0884

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human Mi2-α expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 1107

Synonyms

CHD3; Chromodomain-helicase-DNA-binding protein 3; CHD-3; ATP-dependent helicase CHD3; Mi-2 autoantigen 240 kDa protein; Mi2-alpha; Zinc finger helicase; hZFH

Research area

Epigenetics and nuclear signaling; Immunology

Target protein

CHD3

Recommended dilution

Application Dilution
FC 1:200 - 1:400
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using Mi2-Alpha Monoclonal antibody against HeLa (1) K562 (2) Jurkat (3) NTERA-2 (4) HEK293 (5) Raji (6) cell lysate and mouse brain (7) tissue lysate.
Immunohistochemistry analysis of paraffin-embedded colon cancer tissues with DAB staining using Mi2-Alpha Monoclonal antibody.
Immunofluorescence analysis of Hela cells using Mi2-Alpha Monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye.
Flow cytometric analysis of K562 cells using Mi2-Alpha Monoclonal antibody (green) and negative control (purple).

Protocols

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

Newsletter

Sign up

Newsletter

Sign up