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Home > Product > Antibody > MMP-1 Monoclonal Antibody

MMP-1 Monoclonal Antibody

MMP-1 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Product overview

Full product name

Interstitial collagenase

Code

BT-MCA0889

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human MMP-1 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 4312

Synonyms

MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1

Research area

Signal transduction; Cancer; Cell biology; Cardiovascular

Target protein

MMP1

Recommended dilution

Application Dilution
FC 1:200 - 1:400
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using MMP-1 Monoclonal antibody against HEK293 (1) and MMP1-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemistry analysis of paraffin-embedded human cervical cancer tissues (left) and human kidney cancer tissues (right) with DAB staining using MMP-1 Monoclonal antibody.
Immunofluorescence analysis of Hela cells using MMP-1 Monoclonal antibody. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Flow cytometric analysis of Hela cells using MMP-1 Monoclonal antibody (green) and negative control (purple).

Protocols

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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