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Home > Product > Antibody > MSH2 Monoclonal Antibody

MSH2 Monoclonal Antibody

MSH2 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

DNA mismatch repair protein Msh2

Code

BT-MCA0897

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human MSH2 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 4436

Synonyms

MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2

Research area

Epigenetics and nuclear signaling; Cancer

Target protein

MSH2

Recommended dilution

Application Dilution
ELISA 1:10000
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using MSH2 Monoclonal antibody against HeLa (1) A549 (2) A431 (3) and HEK293 (4) cell lysate.
Immunohistochemistry analysis of paraffin-embedded human breast cancer (left) and lung cancer (right) tissues, showing nuclear localization with DAB staining using MSH2 Monoclonal antibody.
Confocal immunofluorescence analysis of Hela cells using MSH2 Monoclonal antibody (green), showing nuclear localization. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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