Product overview
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Immunogen
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Background
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14|21)(q11.2|q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
Uniprot accession
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Gene ID
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Target protein
Recommended dilution
| Application | Dilution |
|---|---|
| ELISA | 1:10000 |
| IF | 1:200 - 1:1000 |
| IHC | 1:200 - 1:1000 |
| WB | 1:500 - 1:2000 |
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