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Home > Product > Antibody > OTX2 Monoclonal Antibody

OTX2 Monoclonal Antibody

OTX2 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

Homeobox protein OTX2

Code

BT-MCA0962

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human OTX2 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 5015

Synonyms

OTX2; Homeobox protein OTX2; Orthodenticle homolog 2

Research area

Epigenetics and nuclear signaling; Developmental biology; Stem cells; Neuroscience

Target protein

OTX2

Recommended dilution

Application Dilution
ELISA 1:10000
IF 1:200 - 1:1000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using OTX2 Monoclonal antibody against HepG2 (1) Jurkat (2) and NTERA-2 (3) cell lysate.
Immunohistochemistry analysis of paraffin-embedded colon tissues (left) and colon cancer tissues (right) with DAB staining using OTX2 Monoclonal antibody.
Immunofluorescence analysis of U251 cells using OTX2 Monoclonal antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Protocols

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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