Product overview
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Immunogen
Purification
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Background
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Uniprot accession
Molecular weight
Gene ID
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Target protein
Recommended dilution
Application | Dilution |
---|---|
ELISA | 1:10000 |
WB | 1:500 - 1:2000 |
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