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Home > Product > Antibody > p63 Monoclonal Antibody

p63 Monoclonal Antibody

p63 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat, Monkey

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat,Monkey

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Tumor protein 63

Code

BT-MCA0980

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Synthesized peptide of human p63.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)| split-hand/foot malformation 4 (SHFM4)| ankyloblepharon-ectodermal defects-cleft lip/palate| ADULT syndrome (acro-dermato-ungual-lacrim

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 8626; Mouse: 22061; Rat: 246334

Synonyms

TP63; KET; P63; P73H; P73L; TP73L; Tumor protein 63; p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51

Research area

Epigenetics and nuclear signaling; Cell biology; Cancer

Target protein

TP63

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using p63 Monoclonal antibody against A431 (1) HeLa (2) Jurkat (3) THP-1 (4) NIH/3T3 (5) Cos7 (6) and PC-12 (7) cell lysate.
Immunohistochemistry analysis of paraffin-embedded ovarian cancer (left) and lung cancer (right) with DAB staining using p63 Monoclonal antibody.

Protocols

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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