Pinch-1 Monoclonal Antibody

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Home > Product > Antibody > Pinch-1 Monoclonal Antibody

Pinch-1 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IF, ICC, FCM, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IF, ICC, FCM, ELISA

Product overview

Full product name

LIM and senescent cell antigen-like-containing domain protein 1

Code

BT-MCA1033

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human Pinch-1 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;

Molecular weight

N/A

Gene ID

Human: 3987

Synonyms

LIMS1; PINCH; PINCH1; LIM and senescent cell antigen-like-containing domain protein 1; Particularly interesting new Cys-His protein 1; PINCH-1; Renal carcinoma antigen NY-REN-48

Research area

Others

Target protein

LIMS1

Recommended dilution

Application	Dilution
ELISA	1:10000
FC	1:200 - 1:400
IF	1:200 - 1:1000
WB	1:500 - 1:2000

Images

Western Blot analysis using Pinch-1 Monoclonal antibody against A549 (1) Jurkat (2) and HeLa (3) cell lysate.

Immunofluorescence analysis of HepG2 cells using Pinch-1 Monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Flow cytometric analysis of Hela cells using Pinch-1 Monoclonal antibody (blue) and negative control (red).

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

50ul

$180.00
100ul

$300.00

Add to Cart

Lead time: Within one week

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