PP2B-A Alpha Monoclonal Antibody

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Home > Product > Antibody > PP2B-A Alpha Monoclonal Antibody

PP2B-A Alpha Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Mouse,Rat

Applications: WB

Product overview

Full product name

Serine,threonine-protein phosphatase 2B catalytic subunit alpha isoform

Code

BT-MCA1049

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant human PP2B-Aα protein fragments expressed in E.coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage

-20°C for one year

Background

Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 Fe(3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.,online information:Calcineurin entry,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.,

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

N/A

Gene ID

Human: 5530; Mouse: 19055; Rat: 24674

Synonyms

PPP3CA; CALNA; CNA; Serine; threonine-protein phosphatase 2B catalytic subunit alpha isoform; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform

Research area

Signal transduction; Immunology

Target protein

PPP3CA

Recommended dilution

Application	Dilution
WB	1:1000 - 1:2000

Images

Western Blot analysis using PP2B-AAlpha Monoclonal antibody against A431. HeLa cell lysate .

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

50ul

$180.00
100ul

$300.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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