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Background
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Uniprot accession
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Target protein
Recommended dilution
| Application | Dilution |
|---|---|
| ELISA | 1:10000 |
| WB | 1:500 - 1:2000 |
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