Product overview
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Immunogen
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Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Uniprot accession
Molecular weight
Gene ID
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Target protein
Recommended dilution
Application | Dilution |
---|---|
ELISA | 1:10000 |
IHC | 1:200 - 1:1000 |
WB | 1:500 - 1:2000 |
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