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Home > Product > Antibody > TRIM5 Alpha Monoclonal Antibody

TRIM5 Alpha Monoclonal Antibody

TRIM5 Alpha Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Tripartite motif-containing protein 5

Code

BT-MCA1231

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human TRIM5α expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 85363

Synonyms

TRIM5; RNF88; Tripartite motif-containing protein 5; RING finger protein 88

Research area

Epigenetics and nuclear signaling; Immunology

Target protein

TRIM5

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using TRIM5Alpha Monoclonal antibody against human breast carcinoma tissue lysate.
Immunohistochemistry analysis of paraffin-embedded human metastatic adenocarcinoma(A) and stomach adenocarcinoma (B), showing cytoplasmic localization with AEC staining (A) and DAB staining(B) using TRIM5Alpha Monoclonal antibody.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

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Lead time: Within one week

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