ZAP-70 Monoclonal Antibody

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Home > Product > Antibody > ZAP-70 Monoclonal Antibody

ZAP-70 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Tyrosine-protein kinase ZAP-70

Code

BT-MCA1307

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human ZAP-70 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;

Molecular weight

N/A

Gene ID

Human: 7535

Synonyms

ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase

Research area

Others

Target protein

ZAP70

Recommended dilution

Application	Dilution
ELISA	1:10000
IHC	1:200 - 1:1000
WB	1:500 - 1:2000

Images

Western Blot analysis using ZAP-70 Monoclonal antibody against Jurkat cell lysate (1).

Immunohistochemistry analysis of paraffin-embedded human lymph tumor, showing cytoplasmic localization with DAB staining using ZAP-70 Monoclonal antibody.

Protocols

> Protocol Booklet

Customer reviews and Q&As

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Datasheet

Product size

Price

50ul

$180.00
100ul

$300.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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