CENP-M Polyclonal Antibody

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Home > Product > Antibody > CENP-M Polyclonal Antibody

CENP-M Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: IHC-p, IF, WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: IHC-p, IF, WB

Product overview

Full product name

CENP-M

Code

BT-AP01502

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human CENP-M

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;

Gene ID

Human: 79019

Synonyms

CENP-M; Centromere protein M; CENP-M; Interphase centromere complex protein 39; Proliferation-associated nuclear element protein 1

Research area

Epigenetics and nuclear signaling

Target protein

CENPM

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 50 - 1: 200

Images

Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

Add to Cart

Lead time: Within one week

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