ATM(Phospho Ser1987) Rabbit Polyclonal Antibody

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Home > Product > Antibody > ATM(Phospho Ser1987) Rabbit Polyclonal Antibody

ATM(Phospho Ser1987) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

ATM

Code

BT-AP06214

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human ATM (Phospho Ser1987)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder.

Uniprot accession

Human:;Mouse:;

Molecular weight

336160

Gene ID

Human: 472; Mouse: 11920

Synonyms

ATM ;Phospho Ser1987; Serine-protein kinase ATM; EC 2.7.11.1; Ataxia telangiectasia mutated; A-T mutated

Research area

Epigenetics and nuclear signaling; Cancer

Target protein

ATM

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000
ELISA	1: 5000 - 1: 20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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