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Home > Product > Antibody > BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody

BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody

BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

Product overview

Full product name

BAP1

Code

BT-AP06274

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human BAP1 (Ser592)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition| the enzyme may be involved in regulation of transcription| regulation of cell cycle and growth| response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)| which involves increased risk of cancers including malignant mesothelioma| uveal melanoma and cutaneous melanoma.

Uniprot accession

Gene ID

Human: 8314; Mouse: 104416; Rat: 306257

Synonyms

BAP1 ;Ser592; Ubiquitin carboxyl-terminal hydrolase BAP1; EC 3.4.19.12; BRCA1-associated protein 1; Cerebral protein 6

Research area

Cancer; Cell biology; Epigenetics and nuclear signaling

Target protein

BAP1

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000

Protocols

Customer reviews and Q&As

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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

Add to Cart

Lead time: Within one week

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