Full product name
BMAL2
Code
BT-AP06372
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human BMAL2
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Uniprot accession
Molecular weight
69960
Gene ID
Human: 56938; Mouse: 272322
Synonyms
BMAL2
Research area
Cardiovascular; Epigenetics and nuclear signaling; Neuroscience
Target protein
ARNTL2
