IGF-IR(Phospho Tyr1165/Y1166) Polyclonal Antibody

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Home > Product > Antibody > IGF-IR(Phospho Tyr1165/Y1166) Polyclonal Antibody

IGF-IR(Phospho Tyr1165/Y1166) Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat, Monkey

Applications: WB, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, ELISA

Product overview

Full product name

Insulin-like growth factor 1 receptor

Code

BT-AP06683

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166. AA range:1131-1180

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

154793

Gene ID

Human: 3480; Mouse: 16001; Rat: 25718

Synonyms

Insulin-like growth factor 1 receptor; IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Research area

Signal Transduction

Target protein

IGF1R

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 20000

Images

Western Blot analysis of various cells using Phospho-IGF-IR (Y1165/Y1166) Polyclonal Antibody diluted at 1:500

Western Blot analysis of COS7 cells using Phospho-IGF-IR (Y1165/Y1166) Polyclonal Antibody diluted at 1:500

Western blot analysis of lysates from 293 cells treated with Insulin, using IGF1R (Phospho-Tyr1165/Tyr1166) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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