NMDA Epsilon 1/2(Phospho Tyr1246/1252) Polyclonal Antibody

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Home > Product > Antibody > NMDA Epsilon 1/2(Phospho Tyr1246/1252) Polyclonal Antibody

NMDA Epsilon 1/2(Phospho Tyr1246/1252) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

Glutamate [NMDA] receptor subunit epsilon-1/2

Code

BT-AP07316

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human NMDAR2A/B around the phosphorylation site of Tyr1246/1252. AA range:1216-1265

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Rat:;

Molecular weight

165283;166367

Gene ID

Human: 2903/2904; Mouse: 14811/14812; Rat: 24409/24410

Synonyms

Glutamate [NMDA] receptor subunit epsilon-1/2; GRIN2A; NMDAR2A; Glutamate [NMDA; receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A; hNR2A; GRIN2B; NMDAR2B; Glutamate [NMDA; receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; N

Research area

Neuroscience

Target protein

GRIN2A

Recommended dilution

Application	Dilution
IHC-p	1: 100 - 1: 300
IF	1: 200 - 1: 1000
ICC	1: 200 - 1: 1000
ELISA	1: 10000

Images

Immunofluorescence analysis of HUVEC cells, using NMDAR2A/B (Phospho-Tyr1246/1252) Antibody. The picture on the right is blocked with the phospho peptide.

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4°C overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Immunohistochemistry analysis of paraffin-embedded human brain, using NMDAR2A/B (Phospho-Tyr1246/1252) Antibody. The picture on the right is blocked with the phospho peptide.

Western blot analysis of NMDAR2A/B (Phospho-Tyr1246/1252) Antibody. The lane on the right is blocked with the NMDAR2A/B (Phospho-Tyr1246/1252) peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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