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Home > Product > Antibody > Trk A(Phospho Tyr496) Polyclonal Antibody

Trk A(Phospho Tyr496) Polyclonal Antibody

Trk A(Phospho Tyr496) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IF, ICC, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF, ICC, ELISA

Product overview

Full product name

High affinity nerve growth factor receptor

Code

BT-AP01748

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Trk A around the phosphorylation site of Tyr496. AA range:471-520

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that| upon neurotrophin binding| phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain| anhidrosis| self-mutilating behavior| mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found| but only three have been characterized to date.

Uniprot accession

Molecular weight

87497

Gene ID

Human: 4914; Mouse: 18211; Rat: 59109

Synonyms

High affinity nerve growth factor receptor; NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A;

Research area

Neuroscience; Cancer; Metabolism

Target protein

NTRK1

Recommended dilution

Application Dilution
IF 1: 200 - 1: 1000
ICC 1: 200 - 1: 1000
ELISA 1: 5000

Images

Immunofluorescence analysis of NIH/3T3 cells, using Trk A (Phospho-Tyr496) Antibody. The picture on the right is blocked with the phospho peptide.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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