IGF2R(Phospho-Ser2484) Polyclonal Antibody

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Home > Product > Antibody > IGF2R(Phospho-Ser2484) Polyclonal Antibody

IGF2R(Phospho-Ser2484) Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC-p, IF, WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC-p, IF, WB

Product overview

Full product name

IGF2R

Code

BT-AP08854

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human IGF2R (Phospho-Ser2484)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions| including in the intracellular trafficking of lysosomal enzymes| the activation of transforming growth factor beta| and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however| imprinting of the human gene may be polymorphic| as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).

Uniprot accession

Human:;

Gene ID

Human: 3482

Synonyms

IGF2R ;Phospho-Ser2484; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD antigen CD222

Research area

Immunology; Signal transduction; Tags & cell markers

Target protein

IGF2R

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 50 - 1: 200

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

Add to Cart

Lead time: Within one week

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