DAB2 Rabbit Polyclonal Antibody

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Home > Product > Antibody > DAB2 Rabbit Polyclonal Antibody

DAB2 Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

Product overview

Full product name

DAB2

Code

BT-AP08887

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human DAB2

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.333% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells| but is down-regulated or absent from ovarian carcinoma cell lines| suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;Rat:;

Gene ID

Human: 1601; Mouse: 13132; Rat: 79128

Synonyms

DAB2; Disabled homolog 2; DOC-2; Differentially-expressed protein 2)

Research area

Epigenetics and nuclear signaling; Signal transduction

Target protein

DAB2

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000

Images

Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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