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Home > Product > Antibody > IkB alpha Rabbit Polyclonal Antibody

IkB alpha Rabbit Polyclonal Antibody

IkB alpha Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF

Product overview

Full product name

NF-kappa-B inhibitor alpha

Code

BT-AP02141

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Recombinant Protein of IkB α

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the NF-kappa-B inhibitor family| which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Uniprot accession

Gene ID

Human: 4792

Synonyms

NF-kappa-B inhibitor alpha (I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3); NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3)

Research area

Cancer; Epigenetics and nuclear signaling; Immunology; Signal transduction

Target protein

NFKBIA

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 50 - 1: 300
ELISA 1: 20000

Images

Immunohistochemical analysis of paraffin-embedded Rat Kidney Tissue using IkB α Rabbit pAb diluted at 1:200
Immunohistochemical analysis of paraffin-embedded Human Stomach Tissue using IkB α Rabbit pAb diluted at 1:200
Western blot analysis of 1) Hela Cell Lysate, 2)PC12 Cell Lysate, 3) 3T3 Cell Lysate using IkB α Rabbit pAb diluted at 1:1000.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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