IKK alpha/beta(Phospho Ser180/181) Polyclonal Antibody

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Home > Product > Antibody > IKK alpha/beta(Phospho Ser180/181) Polyclonal Antibody

IKK alpha/beta(Phospho Ser180/181) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Inhibitor of nuclear factor kappa-B kinase subunit alpha

Code

BT-AP09008

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta around the phosphorylation site of Ser180/181. AA range:151-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein| a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex| phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway| thereby activating the transcription factor.

Uniprot accession

Human:;Rat:;

Molecular weight

84654;86564

Gene ID

Human: 1147/3551; Mouse: 16150; Rat: 84351

Synonyms

Inhibitor of nuclear factor kappa-B kinase subunit alpha; CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B

Research area

Cancer; Cardiovascular; Cell biology; Signal transduction; Immunology

Target protein

CHUK

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
ELISA	1: 20000

Images

Immunohistochemistry analysis of paraffin-embedded human heart, using IKK-alpha/beta (Phospho-Ser180/181) Antibody. The picture on the right is blocked with the phospho peptide.

Western Blot analysis of various cells using Phospho-IKKα/β (S180/181) Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from HepG2 cells treated with TNF 20ng/ml 5', using IKK-alpha/beta (Phospho-Ser180/181) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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