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Home > Product > Antibody > NFATc4(Phospho Ser168/S170) Polyclonal Antibody

NFATc4(Phospho Ser168/S170) Polyclonal Antibody

NFATc4(Phospho Ser168/S170) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Nuclear factor of activated T-cells cytoplasmic 4

Code

BT-AP09117

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human NFAT3 around the phosphorylation site of Ser168 and Ser170. AA range:136-185

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase| calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells| especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.

Uniprot accession

Molecular weight

95473

Gene ID

Human: 4776; Mouse: 73181

Synonyms

Nuclear factor of activated T-cells cytoplasmic 4; NFATC4; NFAT3; Nuclear factor of activated T-cells; cytoplasmic 4; NF-ATc4; NFATc4; T-cell transcription factor NFAT3; NF-AT3

Research area

Epigenetics and nuclear signaling; Immunology; Signal transduction

Target protein

NFATC4

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 100 - 1: 300
ELISA 1: 5000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NFAT3 (Phospho-Ser168+Ser170) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of NFAT3 (Phospho-Ser168+Ser170) Antibody. The lane on the right is blocked with the NFAT3 (Phospho-Ser168+Ser170) peptide.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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