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Home > Product > Antibody > DHE3 Rabbit Polyclonal Antibody

DHE3 Rabbit Polyclonal Antibody

DHE3 Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

Product overview

Full product name

DHE3

Code

BT-AP02245

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human DHE3

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes glutamate dehydrogenase| which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10| 18 and X.

Uniprot accession

Molecular weight

61380

Gene ID

Human: 2746; Mouse: 14661; Rat: 24399

Synonyms

DHE3

Research area

Cell biology; Metabolism; Signal transduction

Target protein

GLUD1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000

Images

Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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