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Home > Product > Antibody > Insulin Receptor beta(Phospho-Tyr1345) Rabbit Polyclonal Antibody

Insulin Receptor beta(Phospho-Tyr1345) Rabbit Polyclonal Antibody

Insulin Receptor beta(Phospho-Tyr1345) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

Product overview

Full product name

Insulin Receptor beta

Code

BT-AP03116

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human Insulin Receptor β (Tyr1345)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway| which regulates glucose uptake and release| as well as the synthesis and storage of carbohydrates| lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome| Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Uniprot accession

Gene ID

Human: 3643; Mouse: 16337

Synonyms

Insulin Receptor β ;Tyr1345 ; Insulin receptor; IR; EC 2.7.10.1; CD antigen CD220; Insulin receptor subunit alpha; Insulin receptor subunit beta;

Research area

Cardiovascular; Metabolism; Neuroscience ; Signal transduction; Cancer

Target protein

INSR

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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