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Home > Product > Antibody > KPNA6 Rabbit Polyclonal Antibody

KPNA6 Rabbit Polyclonal Antibody

KPNA6 Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

KPNA6

Code

BT-AP10878

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human KPNA6

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.07% sodium azide.

Storage

-20°C for 1 year

Background

Nucleocytoplasmic transport| a signal- and energy-dependent process| takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor| a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran| the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.

Uniprot accession

Gene ID

Human: 23633; Mouse: 16650

Synonyms

KPNA6; Importin subunit alpha-7; Karyopherin subunit alpha-6

Research area

Signal transduction

Target protein

KPNA6

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000

Images

Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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