MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody

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Home > Product > Antibody > MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody

MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

Product overview

Full product name

MCM2

Code

BT-AP03565

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human MCM2 (Ser139)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4| 6| and 7| and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated| and thus regulated by| protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found| but the full-length nature of some variants has not been defined.

Uniprot accession

Human:;Mouse:;

Gene ID

Human: 4171; Mouse: 17216

Synonyms

MCM2 ;Ser139 ; DNA replication licensing factor MCM2; EC 3.6.4.12; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28

Research area

Epigenetics and nuclear signaling

Target protein

MCM2

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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