MDSP

BT-AP11279

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human MDSP

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family| the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames| alternate splicing| and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle| whereas the encoded protein from the downstream ORF was found only in testis. In mouse| a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described| but the full-length sequence of only some were determined.

Human:;Mouse:;

20680

Human: 51207; Mouse: 27389

MDSP

Cell biology; Developmental biology; Signal transduction

DUSP13