MKRN1 Rabbit Polyclonal Antibody

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Blood coagulation
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Epigenetics and nuclear signaling
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Home > Product > Antibody > MKRN1 Rabbit Polyclonal Antibody

MKRN1 Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

MKRN1

Code

BT-AP03621

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human MKRN1

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator| and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21| a cell cycle regulator| and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1| 3| 9| 12 and 20| and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Uniprot accession

Human:;Mouse:;

Molecular weight

53020

Gene ID

Human: 23608

Synonyms

MKRN1

Research area

Cell biology; Epigenetics and nuclear signaling

Target protein

MKRN1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000

Images

Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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