MYPT1/2(Phospho Ser668/Ser618) Rabbit Polyclonal Antibody

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Blood coagulation
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Home > Product > Antibody > MYPT1/2(Phospho Ser668/Ser618) Rabbit Polyclonal Antibody

MYPT1/2(Phospho Ser668/Ser618) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

MYPT1/2

Code

BT-AP11475

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human MYPT1/2 (Phospho Ser668/Ser618)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Regulates myosin phosphatase activity.|PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity). Phosphorylated cooperatively by ROCK1 and CDC42BP on Thr-696. Phosphorylated on upon DNA damage| probably by ATM or ATR.|sequence Contaminating sequence. Potential poly-A sequence.|Contains 6 ANK repeats.|subcellular location:Along actomyosin filaments and stress fibers.|subunit:PP1 comprises a catalytic subunit| PPP1CA| PPP1CB or PPP1CC| and one or several targeting or regulatory subunits. PPP1R12A mediates binding to myosin. Interacts with ARHA and CIT (By similarity). Binds PPP1R12B| ROCK1 and IL16.|

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

113300

Gene ID

Human: 4659; Mouse: 17931; Rat: 116670

Synonyms

MYPT1/2 ;Phospho Ser668/Ser618; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit

Research area

Epigenetics and nuclear signaling; Signal transduction

Target protein

PPP1R12A

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000
ELISA	1: 5000 - 1: 20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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