PKC delta

BT-AP11963

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human PKCδ (Thr505)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters| a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth| apoptosis| and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Human:;Mouse:;Rat:;

Human: 5580; Mouse: 18753; Rat: 170538

PKCδ ;Thr505 ; Protein kinase C delta type; EC 2.7.11.13; Tyrosine-protein kinase PRKCD; EC 2.7.10.2; nPKC-delta

Cancer; Neuroscience; Signal transduction

PRKCD