SHP-2(Phospho-Tyr542) Rabbit Polyclonal Antibody

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Home > Product > Antibody > SHP-2(Phospho-Tyr542) Rabbit Polyclonal Antibody

SHP-2(Phospho-Tyr542) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

Product overview

Full product name

SHP-2

Code

BT-AP12655

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human SHP-2 (Tyr542)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation. This PTP contains two tandem Src homology-2 domains| which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions| such as mitogenic activation| metabolic control| transcription regulation| and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Uniprot accession

Human:;Mouse:;Rat:;

Gene ID

Human: 5781; Mouse: 19247; Rat: 25622

Synonyms

SHP-2 ;Tyr542; Tyrosine-protein phosphatase non-receptor type 11; EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3

Research area

Neuroscience; Signal transduction

Target protein

PTPN11

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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