Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody

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Blood coagulation
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Home > Product > Antibody > Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody

Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

Smad7

Code

BT-AP12686

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human Smad7 (Acetyl Lys70)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding| this complex translocates to the cytoplasm| where it interacts with TGF-beta receptor type-1 (TGFBR1)| leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

46860

Gene ID

Human: 4092; Mouse: 17131; Rat: 81516

Synonyms

Smad7 ;Acetyl Lys70; Mothers against decapentaplegic homolog 7; MAD homolog 7; Mothers against DPP homolog 7; Mothers against decapentaplegic homolog 8; MAD homolog 8; Mothers against DPP homolog 8; SMAD family member 7; SMAD 7; Smad7; hSMAD7

Research area

Epigenetics and nuclear signaling; Signal transduction

Target protein

SMAD7

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000
ELISA	1: 5000 - 1: 20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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