SSX2

BT-AP04911

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human SSX2

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients| and are potentially useful targets in cancer vaccine-based immunotherapy. This gene| and also the SSX1 and SSX4 family members| have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate| GeneID: 727837| located about 45 kb downstream in the opposite orientation on chromosome X.

Human:;

20680

Human: 6757

SSX2

Epigenetics and nuclear signaling

SSX2