UBP18 Rabbit Polyclonal Antibody

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Home > Product > Antibody > UBP18 Rabbit Polyclonal Antibody

UBP18 Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

UBP18

Code

BT-AP05373

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human UBP18

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus| and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions| and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues| indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon| suggesting a function of this protein in downregulating interferon responses| independent of its isopeptidase activity towards ISG15.

Uniprot accession

Human:;Mouse:;

Molecular weight

40920

Gene ID

Human: 11274; Mouse: 24110

Synonyms

UBP18

Research area

Cell biology; Epigenetics and nuclear signaling

Target protein

USP18

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000

Images

Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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