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Home > Product > Antibody > XPC Rabbit Polyclonal Antibody

XPC Rabbit Polyclonal Antibody

XPC Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

Product overview

Full product name

XPC

Code

BT-AP05520

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human XPC

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway| including Xeroderma pigmentosum (XP) A-G and V| Cockayne syndrome (CS) A and B| and trichothiodystrophy (TTD) group A| etc. This component| XPC| plays an important role in the early steps of global genome NER| especially in damage recognition| open complex formation| and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum| a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Uniprot accession

Molecular weight

103400

Gene ID

Human: 7508; Mouse: 22591

Synonyms

XPC

Research area

Epigenetics and nuclear signaling

Target protein

XPC

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000

Images

Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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